New data published in the British Journal of Ophthalmology (BJO) has shown Hoya’s MiyoSmart lens continued to slow myopia progression in children after three years, while patients who switched from single vision lenses had a significant slowdown in their condition.
The ophthalmic lens maker – which released its myopia control spectacle lens in Australia last September – announced the results of a three-year follow up clinical study on its lens incoporating Defocus Incorporated Multiple Segments (D.I.M.S) Technology.
The study, published last month, was conducted by the Centre for Myopia Research at The Hong Kong Polytechnic University and follows up on a two-year study that previously demonstrated children aged eight to 13 wearing its defocus lenses had 60% less myopia progression compared with those wearing single-vision spectacles.
The three-year follow-up study involved 120 children in Asia, comprising 65 from the original MiyoSmart lens group who took part in the previous study and 55 children who moved from a single-vision lens for two years to the MiyoSmart lens in the third year.
At the end of the third year, results in the original MiyoSmart group showed that slowing in myopia progression over time was sustained. Meanwhile, Hoya reported the group that moved from single-vision to MiyoSmart lenses showed “a significant and immediate slowdown” in the progression of their myopia.
Specifically, over three years, spherical equivalent refraction (SER) and axial length (AL) changes in the MiyoSmart group were −0.52±0.69D and 0.31±0.26 mm. These changes were not considered statistically significant over time.
The SER (−0.04±0.38D) and AL (0.08±0.12 mm) changes in those who switched from single vision to MiyoSmart in the third year were less compared with the first year (mean difference=0.45±0.30D, 0.21±0.11 mm, p<0.001) and second year (0.34±0.30D, 0.12±0.10 mm, p<0.001).
“These findings provided further evidence that D.I.M.S lenses slowed myopia progression and axial elongation in children,” the authors noted.
“The optimal age at which treatment should commence is still to be determined and further monitoring is required to ascertain the treatment effect over a longer period. We also plan to follow up on those children who discontinued wearing the DIMS lenses to determine if rebound occurs.”
Hoya Vision Care chief technology officer Mr Griff Altmann said the results of the three-year follow-up study are positive and provide evidence that the lens continues to slow myopia progression in children, including “the impressive results when switching from a single vision lens”.
“As myopia in children is on the rise globally, Hoya Vision Care is proud to be a leader in developing a safe, easy and effective way to manage the growing problem,” he said.
Hoya developed the MiyoSmart lens with The Hong Kong Polytechnic University.
The three-year study data published in the BJO can be found here.