Australia's Leading Ophthalmic Magazine Since 1975

     Free Sign Up     

Australia's Leading Ophthalmic Magazine Since 1975

     Free Sign Up     
Soapbox

Could MIGS replace trabeculectomy?

02/05/2019
Share:
Over the last several years Minimally Invasive Glaucoma Surgery (MIGS) devices have become important parts of an ophthalmologist’s armamentarium.

These devices provide the means by which aqeous can bypass areas of outflow limitation with less tissue manipulation and fewer severe complications than traditional trabeculectomy. Due to these perceived benefits, general ophthalmologists and glaucoma subspecialists are increasingly making use of MIGS.

This prompts one to ask: Is trabeculectomy now completely outdated?

There are a number of reasons why trabeculectomy has long been considered the gold standard for the treatment of uncontrolled glaucoma. Primarily, it has produced effective, long-term results. One of the longest-term studies shows an 88% qualified success rate, even after 20 years. In comparison, few MIGS studies have extended beyond 36 months.

Trabeculectomy is also highly effective at lowering eye pressure. In the most recent studies comparing trabeculectomy to tube shunt implantation, trabeculectomy has ultimately resulted in lower levels of intraocular pressure (IOP). For patients with advanced glaucoma requiring low eye pressure targets, trabeculectomy is often required.

Secondly, trabeculectomy does not require a specially designed device. MIGS devices increase surgical expense and are not without the risk of complications. For example, some degree of hyphaema is not uncommon in MIGS procedures, and cases of stent erosion and endophthalmitis have also been reported for the XEN stent.

"Despite its challenges, it is not difficult to understand why MIGS has increased in popularity."

Furthermore, following the recall of the CyPass suprachoroidal stent due to concerns of its long-term effect on corneal endothelial cells, questions are being raised regarding the long-term safety of MIGS devices.

The emergence of MIGS also raises a secondary issue over doctors maintaining their operative proficiency. If trabeculectomies are performed less frequently, ophthalmologists could become deskilled in this area.

Australia is an important training centre for international fellows. In developing countries where cost limits the availability of MIGS, trabeculectomy will remain a critical procedure for some time. Therefore, trabeculectomies remain important in Australia to ensure skills are maintained and training is available to those who need it.

Despite these challenges, it is not difficult to understand why MIGS has increased in popularity. Prior to its introduction there was no intermediary step between Selective Laser Trabeculoplasty (SLT) and glaucoma filtration surgery. Most ophthalmologists who regularly perform trabeculectomies understand the complexity and extensive follow up required to manage outcomes.

large leaderboard
advertisement

For instance, studies have reported a five-year reoperation rate of 25% for trabeculectomy. The technical demand required to prevent and manage complications has seen trabeculectomy increasingly being performed by ophthalmologists with glaucoma subspecialist training.

MIGS has provided a bridge between medication or laser treatment and glaucoma filtration surgery. On one side, ophthalmologists are increasingly utilising trans-trabecular stents at time of cataract surgery for glaucoma patients with inadequately controlled IOP or an intolerance to eye drops. On the other, the XEN filtration stent is being adopted by more ophthalmologists with glaucoma subspecialist interest as an alternative to trabeculecotmy with reduced risks.

Importantly, MIGS have also prompted an evolution of the surgical approach to glaucoma. This will see future incremental improvements to MIGS devices, making them safer and more effective. The recent Medical Research Futures Fund directed to the development of Australian medical devices might stimulate further progress in this area.

In summary, MIGS devices have given ophthalmologists an increased range of options for treating glaucoma, but it is far too soon to consider trabeculectomy an obsolete procedure. Both procedures will still have their place in an ophthalmologist’s toolbox for some time. Although, current trends and advances in MIGS could change this in the not too distant future.

Name: Dr George Kong
Qualifications: MBBS BMedSci PhD
Workplace: Royal Victorian Eye and Ear Hospital & Mount Waverley Eye Surgeons
Special interests: Glaucoma subspecialist & general ophthalmologist
Conflict of interest: None

 

large leaderboard
advertisement





rectangle
advertisement
Editor's Suggestion
Hot Stories

rectangle
advertisement


OR
 

Subscribe for Insight in your Inbox

Get Insight with the latest in industry news, trends, new products, services and equipment!